A "Polypill" describes a daily pill which may contain blood pressure lowering drugs, statins, aspirin and folic acid. A recent small trial showed that a daily Polypill regimen reduced blood pressure by 11% and cholesterol by 39% for over 50’s (Wald et al 2012).
The polypill scenario has been discussed for some time as a potential population level cardiovascular disease prevention strategy.
Certain key factors which will dictate whether a cardiovascular polypill scenario would influence cardiovascular mortality rates significantly in the UK include
Is there sufficient evidence from larger scale clinical trials that polypills can work effectively?
The polypill would have to be deemed cost effective to be implemented at the population level
The long term adherence of a daily treatment regimen in the population would have to be sufficiently high.